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Study identifier: NCT03409458 Synced from ClinicalTrials.gov · July 28, 2026
● Completed

A Dose Escalation and Confirmation Study of PT-112 in Advanced Solid Tumors in Combination With Avelumab

Condition: Non-Small Cell Lung Cancer (NSCLC)  ·  Sponsor: Promontory Therapeutics Inc.

PhasePhase 1/Phase 2
Planned participants68
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a Phase 1/2, open-label, multi-center, non-randomized, dose-escalation study of PT-112 in combination with the anti-PD-L1 antibody, avelumab, in selected advanced solid tumors. The study is to be conducted in two parts: the Dose Escalation Phase of PT-112 within the combination and the Dose Confirmation Phase in patients with non-small cell lung cancer who will be treated at the RP2D.

This description comes directly from the study's public registry record.

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Contact details are listed per location below or on the registry record.

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Locations (6)

ArizonaPhoenix, Arizona, United States
ColoradoAurora, Colorado, United States
FloridaJacksonville, Florida, United States
MinnesotaRochester, Minnesota, United States
University of Texas MD Anderson Cancer CenterHouston, Texas, United States
LausanneLausanne, Switzerland

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Source record: clinicaltrials.gov/study/NCT03409458