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Study identifier: NCT03406247 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Adjuvant Immunotherapy After Salvage Surgery in Head and Neck Squamous Cell Carcinoma

Condition: Head and Neck Squamous Cell Carcinoma  ·  Sponsor: Gustave Roussy, Cancer Campus, Grand Paris

PhasePhase 2
Planned participants140
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Two randomized trials of reirradiation after salvage surgery have been conducted by the GETTEC and GORTEC collaborative groups, both members of the French HN Intergroup: The first trial compared reirradiation and a "wait and see attitude" and was published in 2008 \[1\]. The second trial compared two modalities of reirradiation. Our hypothesis is that adjuvant treatment with immunotherapy will lead to a DFS similar to that observed in previous trials of post-operative reirradiation with possibly lower toxicity.

This description comes directly from the study's public registry record.

Talk to the study team

Alix MARHIC, MD  ·  +33 (0)1 42 11 42 11  ·  alix.marhic@gustaveroussy.fr

Elodie LECERF  ·  +33 (0)1 42 11 42 11  ·  elodie.lecerf@gustaveroussy.fr

Always discuss trial participation with your own doctor first.

Locations (1)

Gustave RoussyVillejuif, Val De Marne, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT03406247