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Study identifier: NCT03383575 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Azacitidine and Enasidenib in Treating Patients With IDH2-Mutant Myelodysplastic Syndrome

Condition: Acute Myeloid Leukemia · Blasts 20-30 Percent of Bone Marrow Nucleated Cells · Chronic Myelomonocytic Leukemia  ·  Sponsor: M.D. Anderson Cancer Center

PhasePhase 2
Planned participants63
Who can joinAll sexes, 12 Years to no upper limit
Healthy volunteersNo

About this study

This phase II trial studies the side effects and how well azacitidine and enasidenib work in treating patients with IDH2-mutant myelodysplastic syndrome. Azacitidine and enasidenib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth.

This description comes directly from the study's public registry record.

Talk to the study team

Courtney DiNardo, MD  ·  713-794-1141  ·  cdinardo@mdanderson.org

Always discuss trial participation with your own doctor first.

Locations (3)

Johns Hopkins University/Sidney Kimmel Cancer CenterBaltimore, Maryland, United StatesActive Not Recruiting
Cleveland Clinic FoundationCleveland, Ohio, United StatesActive Not Recruiting
M D Anderson Cancer CenterHouston, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT03383575