Condition: Allogeneic Hematopoietic Stem Cell Transplantation · Sponsor: Central Hospital, Nancy, France
The study concerns donors and patients receiving allogeneic stem cell haematopoietic transplantation. The aim of the study is to analyse HSC graft content in immune effector T (naive, memory, activated, exhausted) and immunoregulatory cell subtypes (Tregs, iNKT, MDSC) and correlate the results with post-transplant immune reconstitution of those different cell subtypes and clinical events (graft-versus-host-disease, relapse, infections). An ancillary study will focus on the impact of microbiota dysbiosis on post-transplant immune response and regulatory cell subsets.
This description comes directly from the study's public registry record.
Marie-Thérèse RUBIO, PU-PH · 0383153257 · m.rubio@chru-nancy.fr
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| CHRU de Nancy | Vandœuvre-lès-Nancy, France | Recruiting |
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Source record: clinicaltrials.gov/study/NCT03357172