← Eichor
Study identifier: NCT03340129 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Anti-PD 1 Brain Collaboration + Radiotherapy Extension (ABC-X Study)

Condition: Melanoma Stage Iv  ·  Sponsor: Melanoma Institute Australia

PhasePhase 2
Planned participants218
Who can joinAll sexes, 18 Years to 120 Years
Healthy volunteersNo

About this study

This is a phase II, open label, randomised trial of ipilimumab and nivolumab with concurrent intracranial stereotactic radiotherapy versus ipilimumab and nivolumab alone in patients with asymptomatic, untreated melanoma brain metastases.

This description comes directly from the study's public registry record.

Talk to the study team

Georgina V Long, MBBS PhD  ·  +61 2 9911 7200  ·  info@melanoma.org.au

Maria Gonzalez, RN MHSc  ·  +61 2 9911 7200  ·  maria.gonzalez@melanoma.org.au

Always discuss trial participation with your own doctor first.

Locations (9)

Westmead HospitalSydney, New South Wales, AustraliaRecruiting
Calvary Mater NewcastleHospitalWaratah, New South Wales, AustraliaRecruiting
Melanoma Institute AustraliaWollstonecraft, New South Wales, AustraliaRecruiting
Princess Alexandra HospitalWoolloongabba, Queensland, AustraliaRecruiting
Royal Adelaide HospitalAdelaide, South Australia, AustraliaRecruiting
Peter MacCallum Cancer CentreEast Melbourne, Victoria, AustraliaRecruiting
Alfred HospitalMelbourne, Victoria, AustraliaRecruiting
Sir Charles Gairdner HosptialPerth, Western Australia, AustraliaRecruiting
Oslo Univesity Hospital RadiumhospitaletOslo, Oslo, NorwayTerminated

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT03340129