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Study identifier: NCT03326674 Synced from ClinicalTrials.gov · July 28, 2026
● Terminated

Tesetaxel Plus Reduced Dose of Capecitabine vs. Capecitabine in HER2 Negative, HR Positive, LA/MBC

Condition: Breast Cancer  ·  Sponsor: Odonate Therapeutics, Inc.

PhasePhase 3
Planned participants685
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

CONTESSA is a multinational, multicenter, randomized, Phase 3 study of tesetaxel in patients with HER2 negative, HR positive LA/MBC previously treated with a taxane in the neoadjuvant or adjuvant setting. The primary objective of the study is to compare the efficacy of tesetaxel plus a reduced dose of capecitabine versus the approved dose of capecitabine alone based on progression-free survival (PFS) as assessed by the Independent Radiologic Review Committee (IRC). 685 patients were enrolled.

This description comes directly from the study's public registry record.

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Contact details are listed per location below or on the registry record.

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Locations (207)

Ironwood Cancer and Research CentersChandler, Arizona, United States
Cancer Treatment Centers of America - Western Regional Medical CenterGoodyear, Arizona, United States
Arizona Oncology Associates, P.C. - HOPETucson, Arizona, United States
Genesis Cancer CenterHot Springs, Arkansas, United States
Carti Cancer CenterLittle Rock, Arkansas, United States
Pacific Cancer Medical CenterAnaheim, California, United States
CBCC Global Research, Inc.Bakersfield, California, United States
Compassionate Care Research GroupFountain Valley, California, United States
California Cancer Associates for Research and ExcellenceFresno, California, United States
St. Joseph Heritage HealthcareFullerton, California, United States
UCLA Medical CenterLos Angeles, California, United States
Cancer Care - Torrance Memorial Physician NetworkRedondo Beach, California, United States

+ 195 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT03326674