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Study identifier: NCT03312686 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Changes in Esophageal Distensibility With Proton Pump Inhibitors in Patients With Esophageal Eosinophilia: A Pilot Study

Condition: Eosinophilic Esophagitis  ·  Sponsor: Indiana University

PhaseN/A
Planned participants10
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

This pilot study will explore whether treatment of eosinophilic inflammation in the esophagus is associated with an improved distensibility of the esophagus. Furthermore, previous studies of the esophagus using EndoFlip only measured distensibility of the distal esophagus, specifically the distal esophagus and esophagogastric junction. Eosinophilia in EoE has been demonstrated to affect both upper, middle and lower esophagus. The aim is to measure distensibility both proximal and distal, before and after treatment.

This description comes directly from the study's public registry record.

Talk to the study team

Maureen Schilling  ·  maschi@iu.edu

Lainna Cohen  ·  3172780621  ·  larcohen@iu.edu

Always discuss trial participation with your own doctor first.

Locations (2)

Indiana University Health University HospitalIndianapolis, Indiana, United StatesRecruiting
Indiana UniversityIndianapolis, Indiana, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT03312686