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Study identifier: NCT03291470 Synced from ClinicalTrials.gov · July 27, 2026
● Completed

Study to Determine the Efficacy and Safety of TG-C in Subjects With Kellgren/Lawrence Grade 2 or 3 OA of the Knee

Condition: Degenerative Osteoarthritis  ·  Sponsor: Kolon TissueGene, Inc.

PhasePhase 3
Planned participants531
Who can joinAll sexes, 40 Years to no upper limit
Healthy volunteersNo

About this study

A randomized, double-blind, placebo-controlled, multi-center, phase 3 study to determine the efficacy and safety of TG-C in subjects with Kellgren and Lawrence Grade 2 or 3 Osteoarthritis of the Knee, Osteoarthritis Research Society International (OARSI) medial joint space narrowing (JSN) Grade 1 or 2 of the knee joint. TG-C is to be administered by a single intra-articular injection to the damaged joint area via ultrasound guidance. Patients will be followed for 24 months for safety and efficacy.

This description comes directly from the study's public registry record.

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Contact details are listed per location below or on the registry record.

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Locations (27)

Nebojsa SkrepnikTucson, Arizona, United States
Steve SitarAnaheim, California, United States
Stuart SilvermanBeverly Hills, California, United States
Samy MetyasCovina, California, United States
Bassil AishHuntington Beach, California, United States
Peter HansonLa Mesa, California, United States
Duane AndersonSan Diego, California, United States
Miguel TrevinoClearwater, Florida, United States
Jan HommenDoral, Florida, United States
Mira BaronWest Palm Beach, Florida, United States
Richard RadnovichBoise, Idaho, United States
Thomas SchnitzerChicago, Illinois, United States

+ 15 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT03291470