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Study identifier: NCT03257969 Synced from ClinicalTrials.gov · July 29, 2026
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Impact of the DROP Program on the DRP (Drug Related Problems) Related to Oral Anticancer Drugs in Ambulatory Patients with Risk Factors

Condition: Cancer  ·  Sponsor: Hospices Civils de Lyon

PhaseNA
Planned participants248
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The rise of oral anticancer drugs favors outpatient care but exposes patients to new risks compared to injectable chemotherapy at hospital: non-adherence to treatment, inappropriate management of side effects and interactions with other co-prescribed drugs. Latrogenic risk of these treatments is reinforced in older patients with frequent comorbidities, taking multiple pharmaceutical treatments for long periods and followed by several prescribers. The literature reports an emergence of drug related problems (DRP) in more than 90% of patients, with an average number of 0 to 4 per patient. The clinical consequences (reduced efficacy and potentiation of toxicity) are all the more important that outpatient monitoring of treatments prescribed at the hospital remains underdeveloped due to default of coordination between these two settings. Medical care and prevention of these DRP are difficult because of a lack of information and tools shared between hospital and liberal actors. Experiments are developed according to different organizational models, frequently focused on the pharmaceutical analysis of prescriptions, the detection of DRP and their control, but they stay still undervalued. In this context, the French Society of Oncological Pharmacology (SFPO - Société Française de Pharmacie Oncologique) provides to hospital and ambulatory care pharmacists the Oncolien website and proposes to assess the impact of a program of pharmaceutical interventions named DROP. The hypothesis of…

This description comes directly from the study's public registry record.

Talk to the study team

Catherine RIOUFOL, PharmD  ·  04 78 86 43 70  ·  catherine.rioufol@chu-lyon.fr

Laure HUOT, PharmD  ·  04 72 11 57 62  ·  laure.huot@chu-lyon.fr

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Locations (1)

Service pharmaceutique, Unité de Pharmacie Clinique Oncologique, Centre Hospitalier Lyon SudPierre-Bénite, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT03257969