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Study identifier: NCT03254199 Synced from ClinicalTrials.gov · July 28, 2026
● Terminated

A Study to Assess the Safety and Effectiveness of FLX-787 in Subjects With Charcot-Marie-Tooth Disease Experiencing Muscle Cramps.

Condition: Charcot-Marie-Tooth Disease  ·  Sponsor: Flex Pharma, Inc.

PhasePhase 2
Planned participants27
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The COMMIT Study will assess the safety and effectiveness of FLX-787 in men and women with Charcot-Marie-Tooth disease (CMT) experiencing muscle cramps. Participants will be asked to take two study products during the course of the study. One of these study products will be a placebo. Approximately 120 participants in 20 study centers across the United States are expected to take part. Participants will be in the study for approximately 3 months and visit the study clinic 3 times.

This description comes directly from the study's public registry record.

Talk to the study team

Contact details are listed per location below or on the registry record.

Always discuss trial participation with your own doctor first.

Locations (20)

Mayo ClinicScottsdale, Arizona, United States
University of ColoradoAurora, Colorado, United States
Hospital for Special CareNew Britain, Connecticut, United States
University of FloridaGainesville, Florida, United States
Mayo ClinicJacksonville, Florida, United States
University of South FloridaTampa, Florida, United States
University of IowaIowa City, Iowa, United States
University of Kansas Medical CenterKansas City, Kansas, United States
Massachusetts General HospitalBoston, Massachusetts, United States
Brighman and Women's HospitalBoston, Massachusetts, United States
University of MinnesotaMinneapolis, Minnesota, United States
Saint Louis UniversitySt Louis, Missouri, United States

+ 8 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT03254199