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Study identifier: NCT03249337 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Glanatec(R) for Descemet Stripping in Fuch's Endothelial Dystrophy

Condition: Fuchs' Endothelial Dystrophy  ·  Sponsor: Marian Macsai, MD

PhasePhase 4
Planned participants30
Who can joinAll sexes, 18 Years to 91 Years
Healthy volunteersNo

About this study

In brief, the objective of this study is to investigate whether the drug Glanatec ® which is approved in Japan for glaucoma and ocular hypertension, can be used in patients with Fuchs endothelial dystrophy who have had a descemet stripping procedure without endothelial keratoplasty. While some limited data exists as a proof of concept in in vitro or animal studies, and Glanatec® has been successfully used in a recently published case series for this indication, there is insufficient data to show that this drug can be effectively used for corneal cell clearing while maintaining patient safety. The goal of the study is to provide sufficient proof of concept for the use of this drug in patients with FED whose only treatment alternative is to undergo corneal transplant.

This description comes directly from the study's public registry record.

Talk to the study team

Duanny Alva, MPH  ·  847-570-1783  ·  dalva@northshore.org

Marian Macsai, MD  ·  847-657-1936  ·  mmacsai@northshore.org

Always discuss trial participation with your own doctor first.

Locations (1)

NorthShore University HealthSystemGlenview, Illinois, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT03249337