Condition: Sickle Cell Disease · Stem Cell Transplant Complications · Red Blood Cell Disorder · Sponsor: University of Calgary
The aim of this study to evaluate the safety and efficacy of a nonmyeloablative conditioning regimen for allogeneic hematopoietic stem cell transplantation (HSCT) in pediatric patients with sickle cell disease (SCD) who have a matched related major ABO-incompatible donor. The nonmyeloablative regimen will use alemtuzumab, total body irradiation (TBI) and sirolimus for immune suppression. This study will expand the access of HSCT for patients with SCD who are currently not eligible because of donor restrictions.
This description comes directly from the study's public registry record.
Tony Truong, MD, MPH · 403-955-7272 · tony.truong@ahs.ca
Greg Guilcher, MD · 403-955-7272
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| Alberta Children's Hospital | Calgary, Alberta, Canada | Recruiting |
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Source record: clinicaltrials.gov/study/NCT03214354