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Study identifier: NCT03213002 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Oral Capecitabine and Temozolomide (CAPTEM) for Newly Diagnosed GBM

Condition: Glioblastoma Multiforme (GBM) · Glioblastoma · Glioma of Brain  ·  Sponsor: Northwell Health

PhasePhase 1/Phase 2
Planned participants67
Who can joinAll sexes, 18 Years to 74 Years
Healthy volunteersNo

About this study

The purpose of this study is to evaluate the safety and efficacy of administering the medication capecitabine along with temozolomide when you start your monthly regimen of oral temozolomide for the treatment of your newly diagnosed glioblastoma multiforme (GBM). Capecitabine is an oral chemotherapy that is given to patients with other types of cancer. The study will evaluate whether the dosage of 1500 mg/m2 of capecitabine is tolerable after radiation, when taken along with temozolomide. It will also try to determine if the medication capecitabine helps patients respond to treatment for a longer period of time compared to just temozolomide alone, which is the standard of care.

This description comes directly from the study's public registry record.

Talk to the study team

John Boockvar, MD  ·  212-434-3900  ·  jboockvar@northwell.edu

Tamika Wong, MPH  ·  212-434-4836  ·  twong4@northwell.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Lenox Hill Brain Tumor CenterNew York, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT03213002