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Study identifier: NCT03206190 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

The preSPG4 Study - Studying the Prodromal and Early Phase of SPG4

Condition: Hereditary Spastic Paraplegia · Hereditary, Spastic Paraplegia, Autosomal Dominant  ·  Sponsor: University Hospital Tuebingen

PhaseNA
Planned participants200
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

About this study

Study goals 1. Prospective longitudinal data on progression in the natural course of SPG4 in presymptomatic mutation carriers prior to clinical disease onset and in early stages of disease 2. Biomarkers providing objective measures of disease activity

This description comes directly from the study's public registry record.

Talk to the study team

Ludger Schöls, Prof.  ·  +49 7071 / 29  ·  ludger.schoels@uni-tuebingen.de

Always discuss trial participation with your own doctor first.

Locations (1)

University Hospital Tübingen, Center for NeurologyTübingen, GermanyRecruiting

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Source record: clinicaltrials.gov/study/NCT03206190