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Study identifier: NCT03191149 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Testing Osimertinib as a Treatment for Lung Cancers With an EGFR Exon 20 Change

Condition: Advanced Lung Non-Small Cell Carcinoma · Recurrent Lung Non-Small Cell Carcinoma · Stage IIIB Lung Non-Small Cell Cancer AJCC v7  ·  Sponsor: National Cancer Institute (NCI)

PhasePhase 2
Planned participants46
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This phase II trial studies how well osimertinib works in treating patients with non-small cell lung cancer with EGFR exon 20 insertion mutation that is stage IIIB-IV or has come back after a period of improvement (recurrent). Osimertinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

This description comes directly from the study's public registry record.

Talk to the study team

Contact details are listed per location below or on the registry record.

Always discuss trial participation with your own doctor first.

Locations (345)

Anchorage Associates in Radiation MedicineAnchorage, Alaska, United StatesActive Not Recruiting
Anchorage Radiation Therapy CenterAnchorage, Alaska, United StatesActive Not Recruiting
Alaska Breast Care and Surgery LLCAnchorage, Alaska, United StatesActive Not Recruiting
Alaska Oncology and Hematology LLCAnchorage, Alaska, United StatesActive Not Recruiting
Alaska Women's Cancer CareAnchorage, Alaska, United StatesActive Not Recruiting
Anchorage Oncology CentreAnchorage, Alaska, United StatesActive Not Recruiting
Katmai Oncology GroupAnchorage, Alaska, United StatesActive Not Recruiting
Providence Alaska Medical CenterAnchorage, Alaska, United StatesActive Not Recruiting
Fairbanks Memorial HospitalFairbanks, Alaska, United StatesRecruiting
Mercy Hospital Fort SmithFort Smith, Arkansas, United StatesRecruiting
CARTI Cancer CenterLittle Rock, Arkansas, United StatesRecruiting
Providence Saint Joseph Medical Center/Disney Family Cancer CenterBurbank, California, United StatesActive Not Recruiting

+ 333 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT03191149