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Study identifier: NCT03180918 Synced from ClinicalTrials.gov · July 29, 2026
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Male Fertility Preservation Using Cryopreservation of Testicular Tissue Before Highly Gonadotoxic Cancer Treatment

Condition: Childhood Cancer · Fertility Disorders  ·  Sponsor: Gumy-Pause Fabienne

PhaseNA
Planned participants100
Who can joinMale, 3 Months to 18 Years
Healthy volunteersNo

About this study

Background: Due to the remarkable improvement in treatments these last decades, long term survival can be expected in more than 80% of childhood cancer patients. Unfortunately, cancer treatments can be harmful to the gonads and can affect reproductive and endocrine functions. While loss of fertility is a major concern for most patients, sperm cryopreservation should be offered to all pubertal male patients. For prepubertal boys, only the experimental option of testicular biopsy in order to cryopreserve testicular stem cells can be proposed. Primary aims \- To cryopreserve testicular tissue of prepubertal patient receiving highly gonadotoxic oncological treatment. Secondary aims * To cryopreserve testicular tissue after failure of sperm cryopreservation in pubertal patient with high risk of infertility * To create a database in order to record clinical and biological follow-up data * To create a research biobank for future research projects Multicentric study: HUG, CHUV, UKBB

This description comes directly from the study's public registry record.

Talk to the study team

Fabienne Gumy-Pause, Dr  ·  fabienne.gumypause@hcuge.ch

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Locations (3)

UKBBBasel, SwitzerlandRecruiting
Geneva University HospitalsGeneva, SwitzerlandRecruiting
CHUVLausanne, SwitzerlandRecruiting

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Source record: clinicaltrials.gov/study/NCT03180918