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Study identifier: NCT03168802 Synced from ClinicalTrials.gov · July 29, 2026
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MRgFUS and RFA for Treatment of Facet-joint Osteoarthritis Low Back Pain

Condition: Chronic Low Back Pain · Facet Joint Syndrome  ·  Sponsor: Taipei Medical University Hospital

PhaseNA
Planned participants100
Who can joinAll sexes, 20 Years to 79 Years
Healthy volunteersNo

About this study

This is a prospective, randomized, two-arm, phase II study. The purpose of this study is: * To evaluate and compare the efficacy and safety of magnetic resonance-guided focused ultrasound (MRgFUS) and radiofrequency ablation (RFA) for treatment of facet-joint osteoarthritis low back pain. * Determining the effect of the MRgFUS System and RFA for improving functional disabilities and in reducing pain resulting from facet-joint osteoarthritis low back pain. Efficacy will be determined by the level of pain relief (as measured by the Numerical Rating Scale, NRS), decrease in analgesics/opiate, improved quality of life (as measured by the Oswestry Disability Questionnaire, ODQ, and core outcome measures index questionnaire, COMI), pain interference with function (as measured by the Brief Pain Inventory-Interference scale, BPI-QoL), general health status (as measured by the EQ5D), physical exam, X-ray and MRI studies from baseline up to 12-Months post- MRgFUS and radiofrequency treatment. * Evaluate incidence and severity of adverse events associated with the MRgFUS system and RFA used for the treatment of pain resulting from facet-joint osteoarthritis low back pain.

This description comes directly from the study's public registry record.

Talk to the study team

Meng-Huang Wu, MD  ·  227372181  ·  maxwutmu@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Taipei medical university hospitalTaipei, Please Select, TaiwanRecruiting

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Source record: clinicaltrials.gov/study/NCT03168802