Condition: B Acute Lymphoblastic Leukemia · Sponsor: Alliance for Clinical Trials in Oncology
This phase III trial studies the side effects of inotuzumab ozogamicin and how well it works when given with frontline chemotherapy in treating patients with newly diagnosed B acute lymphoblastic leukemia. Inotuzumab ozogamicin is a monoclonal antibody, called inotuzumab, linked to a chemotherapy drug called ozogamicin. Inotuzumab is a form of targeted therapy because it attaches to specific molecules (receptors) on the surface of cancer cells, known as CD22 receptors, and delivers ozogamicin to kill them. Chemotherapy drugs, such as \[intervention\], work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving inotuzumab ozogamicin with chemotherapy may work better in treating young adults with B acute lymphoblastic leukemia.
This description comes directly from the study's public registry record.
Daniel J. DeAngelo, MD, PhD · 617-632-2645 · daniel_deangelo@dfci.harvard.edu
Always discuss trial participation with your own doctor first.
| University of Alabama at Birmingham Cancer Center | Birmingham, Alabama, United States | Active Not Recruiting |
| Anchorage Associates in Radiation Medicine | Anchorage, Alaska, United States | Suspended |
| Anchorage Radiation Therapy Center | Anchorage, Alaska, United States | Suspended |
| Alaska Breast Care and Surgery LLC | Anchorage, Alaska, United States | Suspended |
| Alaska Oncology and Hematology LLC | Anchorage, Alaska, United States | Suspended |
| Alaska Women's Cancer Care | Anchorage, Alaska, United States | Suspended |
| Anchorage Oncology Centre | Anchorage, Alaska, United States | Suspended |
| Katmai Oncology Group | Anchorage, Alaska, United States | Suspended |
| Providence Alaska Medical Center | Anchorage, Alaska, United States | Suspended |
| Fairbanks Memorial Hospital | Fairbanks, Alaska, United States | Suspended |
| Kingman Regional Medical Center | Kingman, Arizona, United States | Suspended |
| Mayo Clinic Hospital in Arizona | Phoenix, Arizona, United States | Suspended |
+ 448 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT03150693