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Study identifier: NCT03137095 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Effects of Chemotherapy on Cognitive Function in Breast Cancer Patients & Non-Cancer Control Subjects With Optional Sub-Study Research Brain MRI

Condition: Cancer Related Cognitive Difficulties · Breast Cancer Female  ·  Sponsor: University of Rochester

PhaseN/A
Planned participants150
Who can joinFemale, 21 Years to no upper limit
Healthy volunteersYes

About this study

Study is enrolling newly diagnosed breast cancer patients about to start chemotherapy and age-matched control participants. The investigator is trying to better understand the prevalence of cognitive difficulties in cancer patients receiving chemotherapy compared to the general population as well as what biological mechanisms may play a role in the development of these difficulties. Patients will be asked to complete six assessments over the course of approximately 5 months. Assessments 1,3, 4.5 and 5 include computerized and paper and pencil cognitive testing as well as blood draws. Assessments 2 and 4 only involve the collection of a blood sample. An optional sub study is offered after Assessment 1. It involves a research brain MRI at Assessment 4.5 and cognitive testing and another research brain MRI at Assessment 6.

This description comes directly from the study's public registry record.

Talk to the study team

Sara Alberti  ·  585-273-3998  ·  Sara_Alberti@urmc.rochester.edu

Tyler Holler  ·  585-273-2950  ·  Tyler_Holler@urmc.rochester.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of RochesterRochester, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT03137095