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Study identifier: NCT03127267 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Efficacy and Safety of Masitinib Versus Placebo in the Treatment of ALS Patients

Condition: Amyotrophic Lateral Sclerosis  ·  Sponsor: AB Science

PhasePhase 3
Planned participants495
Who can joinAll sexes, 18 Years to 81 Years
Healthy volunteersNo

About this study

The objective is to compare the efficacy and safety of masitinib in combination with riluzole versus matched placebo in combination with riluzole for the treatment of Amyotrophic Lateral Sclerosis (ALS).

This description comes directly from the study's public registry record.

Talk to the study team

Clinical Study Coordinator  ·  +33(0)147200014  ·  clinical@ab-science.com

Always discuss trial participation with your own doctor first.

Locations (56)

University of Alabama at BirminghamBirmingham, Alabama, United StatesRecruiting
University of Southern CaliforniaLos Angeles, California, United StatesRecruiting
University of KentuckyLexington, Kentucky, United StatesRecruiting
Johns Hopkins Medicine Brain Science InstituteBaltimore, Maryland, United StatesRecruiting
Lahey Hospital and Medical CenterBurlington, Massachusetts, United StatesRecruiting
University of Virginia Health SystemCharlottesville, Virginia, United StatesRecruiting
University Hospital Leuven (UZ Leuven)Leuven, BelgiumRecruiting
Bispebjerg HospitalCopenhagen, DenmarkRecruiting
CHU de AngersAngers, FranceRecruiting
Groupe Hospitalier Pellegrin TripodeBordeaux, FranceRecruiting
Hôpital neurologique Pierre WertheimerBron, FranceRecruiting
CHU Gabriel MontpiedClermont-Ferrand, FranceRecruiting

+ 44 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT03127267