Condition: Sickle Cell Disease · Sponsor: University of Illinois at Chicago
The study is a Phase II clinical trial. Patients will receive intensity modulated total body irradiation (TBI) at a dose of 3 Gy with standard fludarabine/ i.v. cyclophosphamide conditioning prior to human leukocyte antigen (HLA)-haploidentical hematopoietic stem cell transplant (HSCT). The primary objective of the study is to determine the engraftment at Day +60 following HLA-haploidentical hematopoietic stem cell transplant protocol using immunosuppressive agents and low-dose total body irradiation (TBI) for conditioning and post-transplant cyclophosphamide in patients with sickle cell disease.
This description comes directly from the study's public registry record.
Damiano Rondelli, MD · 312 413-3547 · drond@uic.edu
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| University of Illinois at Chicago | Chicago, Illinois, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT03121001