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Study identifier: NCT03104491 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Inotuzumab Ozogamicin Post-Transplant For Acute Lymphocytic Leukemia

Condition: Acute Lymphocytic Leukemia  ·  Sponsor: Leland Metheny

PhasePhase 1/Phase 2
Planned participants44
Who can joinAll sexes, 16 Years to 75 Years
Healthy volunteersNo

About this study

This study has two phases, Phase I and Phase II. The main goal of the Phase I portion of this research study is to see what doses post-transplant inotuzumab ozogamicin can safely be given to subjects without having too many side effects. The Phase II portion of this study is to see what side effects are seen with medication after transplant. Inotuzumab ozogamicin is a combination of an antibody and chemotherapy which has been shown to have significant activity against relapsed/refractory acute lymphocytic leukemia (ALL). Inotuzumab ozogamicin is considered experimental in this study.

This description comes directly from the study's public registry record.

Talk to the study team

Leland Metheny, MD  ·  1-800-641-2422  ·  CTUReferral@UHhospitals.org

Ron Sobecks, MD  ·  216-444-6833  ·  sobeckr@ccf.org

Always discuss trial participation with your own doctor first.

Locations (7)

The University of Kansas Cancer CenterWestwood, Kansas, United StatesRecruiting
Dana-Farber Cancer InstituteBoston, Massachusetts, United StatesRecruiting
University of Nebraska Medical CenterOmaha, Nebraska, United StatesRecruiting
Memorial Sloan Kettering Cancer CenterNew York, New York, United StatesActive Not Recruiting
University Hospitals Cleveland Medical Center, Case Comprehensive Cancer CenterCleveland, Ohio, United StatesRecruiting
Cleveland Clinic Taussig Cancer institute, Case Comprehensive Cancer CenterCleveland, Ohio, United StatesActive Not Recruiting
The James Cancer Hospital and Solove Research InstituteColumbus, Ohio, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT03104491