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Study identifier: NCT03103932 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Biomarker Guided Discharge of Heart Failure Patients

Condition: Heart Failure; With Decompensation  ·  Sponsor: Ottawa Heart Institute Research Corporation

PhaseNA
Planned participants750
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a multi-centre, single blind, randomized study. Patients admitted to hospital with acute decompensated heart failure will be randomized to biomarker guided discharge algorithm vs usual care in a 2:1 ratio. NTproBNP and other biomarkers will be measured within 24 hours of admission. The NTproBNP results will be used to further stratify participants randomized to the biomarker guided group into lower and medium to higher risk pathways. Biomarkers will be repeated after 2-3 days and again prior to discharge. Specific care pathways will be followed for each of the lower risk and medium-higher risk groups. Biomarkers will be repeated 30 days post discharge. Participants will be followed with a phone call at 3 months and return for a follow up visit at 6 months post discharge for outcome evaluation.

This description comes directly from the study's public registry record.

Talk to the study team

Ermina Moga, MD  ·  613-696-7000  ·  emoga@ottawaheart.ca

Always discuss trial participation with your own doctor first.

Locations (1)

University of Ottawa Heart InstituteOttawa, Ontario, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT03103932