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Study identifier: NCT03093688 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Clinical Safty and Efficacy Study of Infusion of iNKT Cells and CD8+T Cells in Patients With Advanced Solid Tumor

Condition: Non-small Cell Lung Cancer · Small Cell Lung Cancer · Pancreas Cancer  ·  Sponsor: Shanghai Public Health Clinical Center

PhasePhase 1/Phase 2
Planned participants40
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

About this study

Invariant Natural killer T (iNKT) cells are a unique subset of lymphocytes that express homogeneous TCR recognizing KRN7000 which was up-regulated by many kinds of cancer cells. PD-1+CD8+T cells of patients with advanced tumor are most likely tumor-specified. Our hypothesis is that immunotherapy strategy of infusion of iNKT cells and PD-1+CD8+T cells may decrease the tumor burden and improve overall survival. The purpose of this study is to assess the safety and efficacy of treatment of patients with advanced solid tumor by infusing of iNKT cells and PD-1+CD8+T cells.

This description comes directly from the study's public registry record.

Talk to the study team

Yan X Zhang, M.D.  ·  0086-021-37990333  ·  zhangxiaoyan@shaphc.org

Recruiting

Always discuss trial participation with your own doctor first.

Locations (1)

Shanghai Public Health Clinical CenterShanghai, Shanghai Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT03093688