Condition: Hypertension · Pure Autonomic Failure · Multiple System Atrophy · Sponsor: Vanderbilt University Medical Center
Patients with autonomic failure are characterized by disabling orthostatic hypotension (low blood pressure on standing), and at least half of them also have high blood pressure while lying down (supine hypertension). Exposure to heat, such as in hot environments, often worsens their orthostatic hypotension. The causes of this are not fully understood. The purpose of this study is to evaluate whether applying local heat over the abdomen of patients with autonomic failure and supine hypertension during the night would decrease their nocturnal high blood pressure while lying down. This will help us better understand the mechanisms underlying this phenomenon, and may be of use in the treatment of supine hypertension.
This description comes directly from the study's public registry record.
Bonnie K Black, RN · 615-343-6862 · autonomics@vumc.org
Italo Biaggioni, MD · autonomics@vumc.org
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| Autonomic Dysfunction Center/ Vanderbilt University Medical Center | Nashville, Tennessee, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT03042988