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Study identifier: NCT03042221 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Early Rebiopsy to Identify Biomarkers of Tumor Cell Survival Following EGFR, ALK, ROS1 or BRAF TKI Therapy

Condition: Non-Small Cell Carcinoma of Lung, TNM Stage 4 · Non-Small Cell Lung Cancer · EGFR Gene Mutation  ·  Sponsor: University of Colorado, Denver

PhaseN/A
Planned participants100
Who can joinAll sexes, 18 Years to 85 Years
Healthy volunteersNo

About this study

A comparison of baseline tumor characteristics in oncogene-driven cancers to tumor characteristics after early response to Tyrosine Kinase Inhibitor (TKI) targeted treatment will allow identification of early adaptive mechanisms of cell survival. This will facilitate targeting and termination of these survival/ resistance pathways before they develop with rational combinations of therapeutic agents to improve outcomes.

This description comes directly from the study's public registry record.

Talk to the study team

Brandi Kubala  ·  303-724-1657  ·  brandi.kubala@cuanschutz.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of Colorado, Cancer CenterAurora, Colorado, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT03042221