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Study identifier: NCT03020381 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Gait as Predictor of Dementia and Falls. The Gait and Brain Cohort Study

Condition: Gait Apraxia · Mild Cognitive Impairment · Subjective Cognitive Impairment  ·  Sponsor: Manuel Montero Odasso

PhaseN/A
Planned participants600
Who can joinAll sexes, 60 Years to 85 Years
Healthy volunteersYes

About this study

Motor slowing and cognitive slowing are more prevalent as we age. Importantly, the presence of both in an older person increases their risk of having dementia by ten times. Currently, there are no clinically meaningful predictors of progression to dementia in people with mild cognitive impairment (MCI). The main hypothesis is that subtle variations in gait while performing a simple cognitive task is a reliable, easy to perform, and feasible methodology to detect those older adults at higher risk of progression to dementia and also, at higher risk of further mobility decline and falls. Rationale. The Canadian population is aging. According to recent estimates, the proportion of the population aged 65 and older will increase rapidly from 13% in 2005 to 25% by 2031. This increase in proportion is accompanied by a considerable amount of disability and subsequent dependency which has major effects on both the quality of life of older adults and their caregivers, and on the Canadian health care system. An important goal of geriatric medicine is to reduce the gap between life expectancy and disability-free life expectancy by reducing disability and dependency in the later years of life. A substantial portion of this disability stems from two major geriatric syndromes: cognitive impairment and mobility limitation. The ultimate manifestations of these syndromes are dementia and falls. Interestingly, these manifestations often coexist in elderly people: falling is a common geriatric s…

This description comes directly from the study's public registry record.

Talk to the study team

Dr. Manuel Montero Odasso, MD, PhD  ·  5196854292

Always discuss trial participation with your own doctor first.

Locations (1)

Gait and Brain Lab, Parkwood InstituteLondon, Ontario, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT03020381