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Study identifier: NCT03013998 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Study of Biomarker-Based Treatment of Acute Myeloid Leukemia

Condition: Previously Untreated Relapsed Refractory Acute Myeloid Leukemia  ·  Sponsor: Beat AML, LLC

PhasePhase 1/Phase 2
Planned participants3000
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This screening and multi-sub-study Phase 1b/2 trial will establish a method for genomic screening followed by assigning and accruing simultaneously to a multi-study "Master Protocol (BAML-16-001-M1)." The specific subtype of acute myeloid leukemia will determine which sub-study, within this protocol, a participant will be assigned to evaluate investigational therapies or combinations with the ultimate goal of advancing new targeted therapies for approval. The study also includes a marker negative sub-study which will include all screened patients not eligible for any of the biomarker-driven sub-studies. Patients with myeloid malignancies \[e.g. myelodysplastic syndrome (MDS) or other diseases\], will be allowed to enroll to Master protocol if there is an available sub-study.

This description comes directly from the study's public registry record.

Talk to the study team

Ashley Yocum, PhD  ·  301-814-2788  ·  ashley.yocum@BloodCancerUnited.org

Always discuss trial participation with your own doctor first.

Locations (19)

Mayo Clinic ArizonaPhoenix, Arizona, United StatesCompleted
UCLA Ronald Reagan Medical CenterLos Angeles, California, United StatesRecruiting
University of California, San FranciscoSan Francisco, California, United StatesRecruiting
University of ColoradoDenver, Colorado, United StatesCompleted
University of Florida Health Shands Cancer HospitalGainesville, Florida, United StatesCompleted
Mayo Clinic FloridaJacksonville, Florida, United StatesCompleted
Emory UniversityAtlanta, Georgia, United StatesRecruiting
University of ChicagoChicago, Illinois, United StatesRecruiting
University of Kansas Clinical Research CenterFairway, Kansas, United StatesRecruiting
University of Maryland Medical CenterBaltimore, Maryland, United StatesRecruiting
Mayo Clinic MinnesotaRochester, Minnesota, United StatesCompleted
Memorial Sloan Kettering Cancer CenterNew York, New York, United StatesRecruiting

+ 7 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT03013998