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Study identifier: NCT03008291 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

His Bundle Pacing in Bradycardia and Heart Failure

Condition: Bradycardia · Heart Failure  ·  Sponsor: Yong-Mei Cha

PhaseN/A
Planned participants80
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Participants in this study will either have heart failure (HF) and are scheduled to undergo pace maker (PM) implantation, cardiac resynchronization therapy pacemaker (CRT-P), cardiac resynchronization therapy defibrillator (CRT-D) implantation, His bundle pacing (HIBP) or left bundle area pacing (LBAP) (including HIBP/LBAP for patients with HF, for patients who have failed CRT implant or patients who are CRT non-responders), or have atrioventricular (AV) block or bradycardia and are scheduled to undergo dual chamber pacemaker implantation. In this study additional heart rhythm measurements will be collected during the implant procedure to better understand how His bundle and/or parahisian pacing (HISP) effects electrical conduction in the hearts of patients with HF or AV block. The hypothesis is that His bundle or parahisian pacing (HISP) and left bundle area pacing (LBAP) may normalize atrioventricular (AV) conduction with a narrow combination of the Q wave, R wave and S wave (QRS complex) in functional bundle branch block or conduction delay in patients with heart failure (HF).

This description comes directly from the study's public registry record.

Talk to the study team

Yong-Mei Cha, M.D.  ·  (507) 255-2440  ·  ycha@mayo.edu

Brent W Quam  ·  507-422-3235  ·  quam.brent@mayo.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Mayo ClinicRochester, Minnesota, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT03008291