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Study identifier: NCT02991469 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Repeated Dose-finding Study of Sarilumab in Children and Adolescents With Systemic Juvenile Idiopathic Arthritis (SKYPS)

Condition: Juvenile Idiopathic Arthritis  ·  Sponsor: Sanofi

PhasePhase 2
Planned participants51
Who can joinAll sexes, 1 Year to 17 Years
Healthy volunteersNo

About this study

Primary Objective: To describe the pharmacokinetic (PK) profile of sarilumab in patients aged 1-17 years with Systemic Juvenile Idiopathic Arthritis (sJIA) in order to identify the dose and regimen for adequate treatment of this population. Secondary Objective: To describe the pharmacodynamics (PD) profile, the efficacy, and the long term safety of sarilumab in patients with sJIA.

This description comes directly from the study's public registry record.

Talk to the study team

Trial Transparency email recommended (Toll free for US & Canada)  ·  800-633-1610  ·  Contact-Us@sanofi.com

Always discuss trial participation with your own doctor first.

Locations (32)

Investigational Site Number : 0320004San Miguel de Tucumán, Tucumán Province, ArgentinaRecruiting
Investigational Site Number : 0320005Buenos Aires, ArgentinaRecruiting
Investigational Site Number : 1240110Calgary, Alberta, CanadaRecruiting
Investigational Site Number : 2460040Helsinki, FinlandRecruiting
Investigational Site Number : 2500041Bron, FranceRecruiting
Investigational Site Number : 2500042Montpellier, FranceRecruiting
Investigational Site Number : 2500040Paris, FranceRecruiting
Investigational Site Number : 2760064Berlin, GermanyRecruiting
Investigational Site Number : 2760065Berlin, GermanyRecruiting
Investigational Site Number : 2760062Hamburg, GermanyRecruiting
Investigational Site Number : 2760060Sankt Augustin, GermanyRecruiting
Investigational Site Number : 2760063Sendenhorst, GermanyCompleted

+ 20 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT02991469