Condition: Diabetic Nephropathies · Diabetic Glomerulosclerosis · Sponsor: University of Pennsylvania
This is a prospective, observational, cohort study of patients with a clinical diagnosis of diabetes who are undergoing clinically indicated kidney biopsy. The intent is to collect, process, and study kidney tissue and to harvest blood, urine and genetic materials to elucidate molecular pathways and link them to biomarkers that characterize those patients have a rapid decline in kidney function (\> 5 mL/min/1.73m2/year) from those with lesser degrees of kidney function change over the period of observation. High through-put genomic analysis associated with genetic and biomarker testing will serve to identify key potential therapeutic targets for DKD by comparing patients with rapid and slow progression patterns. Each participating clinical site will search for, consent, harvest the biopsy sample, and enroll the participants as required for the TRIDENT protocol.
This description comes directly from the study's public registry record.
Katalin Susztak, MD, PhD · 646-541-4079 · ksusztak@pennmedicine.upenn.edu
Always discuss trial participation with your own doctor first.
| University of Arkansas for Medical Sciences | Little Rock, Arkansas, United States | Recruiting |
| University of Southern California | Los Angeles, California, United States | Active Not Recruiting |
| Stanford University | Palo Alto, California, United States | Recruiting |
| Yale University | New Haven, Connecticut, United States | Recruiting |
| Northwestern University | Chicago, Illinois, United States | Recruiting |
| University of Michigan | Ann Arbor, Michigan, United States | Active Not Recruiting |
| University of New Mexico | Albuquerque, New Mexico, United States | Recruiting |
| Mount Sinai Hospital | New York, New York, United States | Recruiting |
| Columbia University | New York, New York, United States | Active Not Recruiting |
| Albert Einstein College of Medicine | The Bronx, New York, United States | Active Not Recruiting |
| University of North Carolina | Chapel Hill, North Carolina, United States | Recruiting |
| Ohio State University | Columbus, Ohio, United States | Recruiting |
+ 5 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT02986984