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Study identifier: NCT02915198 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes

Condition: Prediabetic State · Atherosclerosis · Metformin  ·  Sponsor: VA Office of Research and Development

PhasePhase 4
Planned participants7410
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This research will help us to learn if the medicine called metformin reduces the risk of death, heart attacks, and/or strokes in Veterans who have pre-diabetes and heart or blood vessel problems.

This description comes directly from the study's public registry record.

Talk to the study team

Gregory G Schwartz, PhD MD  ·  (720) 723-6070  ·  Gregory.Schwartz@va.gov

Kevin Gropp  ·  (720) 857-5659  ·  kevin.gropp@va.gov

Always discuss trial participation with your own doctor first.

Locations (40)

Phoenix VA Health Care System, Phoenix, AZPhoenix, Arizona, United StatesRecruiting
Southern Arizona VA Health Care System, Tucson, AZTucson, Arizona, United StatesRecruiting
Central Arkansas VHS John L. McClellan Memorial Veterans Hospital, Little Rock, ARLittle Rock, Arkansas, United StatesRecruiting
VA Loma Linda Healthcare System, Loma Linda, CALoma Linda, California, United StatesRecruiting
VA Long Beach Healthcare System, Long Beach, CALong Beach, California, United StatesRecruiting
VA Palo Alto Health Care System, Palo Alto, CAPalo Alto, California, United StatesRecruiting
VA San Diego Healthcare System, San Diego, CASan Diego, California, United StatesRecruiting
VA Greater Los Angeles Healthcare System, West Los Angeles, CAWest Los Angeles, California, United StatesRecruiting
Rocky Mountain Regional VA Medical Center, Aurora, COAurora, Colorado, United StatesRecruiting
VA Connecticut Healthcare System West Haven Campus, West Haven, CTWest Haven, Connecticut, United StatesRecruiting
Bay Pines VA Healthcare System, Pay Pines, FLBay Pines, Florida, United StatesRecruiting
North Florida/South Georgia Veterans Health System, Gainesville, FLGainesville, Florida, United StatesRecruiting

+ 28 more locations — full list on the registry record.

Follow this study

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Source record: clinicaltrials.gov/study/NCT02915198