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Study identifier: NCT02897063 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Effects of Midodrine and Droxidopa on Splanchnic Capacitance in Autonomic Failure

Condition: Autonomic Failure · Pure Autonomic Failure · Multiple System Atrophy  ·  Sponsor: Vanderbilt University Medical Center

PhasePhase 1
Planned participants34
Who can joinAll sexes, 40 Years to 80 Years
Healthy volunteersNo

About this study

The purpose of this study is to learn more about the effects of midodrine and droxidopa, two medications used for the treatment of orthostatic hypotension (low blood pressure on standing), on the veins of the abdomen of patients with autonomic failure. The study will be conducted at Vanderbilt University Medical Center, and consists of 2 parts: a screening and 2 testing days. The total length of the study will be about 5 days. About 34 participants will be screened for the study.

This description comes directly from the study's public registry record.

Talk to the study team

Bonnie K Black, RN  ·  615-343-6862  ·  autonomics@vumc.org

Luis E Okamoto, MD  ·  615-936-6119  ·  autonomics@vumc.org

Always discuss trial participation with your own doctor first.

Locations (1)

Autonomic Dysfunction Center/ Vanderbilt University Medical CenterNashville, Tennessee, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT02897063