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Study identifier: NCT02860364 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Comparing Hypothermic Temperatures During Hemiarch Surgery

Condition: Thoracic Aortic Disease  ·  Sponsor: Ottawa Heart Institute Research Corporation

PhaseNA
Planned participants282
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Hypothermic circulatory arrest is an important surgical technique, allowing complex aortic surgeries to be performed safely. Hypothermic circulatory arrest provides protection to cerebral and visceral organs, but may result in longer cardiopulmonary bypass times during surgery, increased risks of bleeding, inflammation, and neuronal injury. To manage these consequences, a trend towards warmer core body temperatures during circulatory arrest has emerged. This trial will randomize patients to either mild (32°C) or moderate (26°C) hypothermia during aortic hemiarch surgery to determine if mild hypothermia reduces the length of cardiopulmonary bypass time and other key measures of morbidity and mortality.

This description comes directly from the study's public registry record.

Talk to the study team

Jehangir Appoo, MD  ·  403-944-2515  ·  jappoo@ucalgary.ca

Alice Black, BSc  ·  613-696-7230  ·  alblack@ottawaheart.ca

Always discuss trial participation with your own doctor first.

Locations (12)

Massachusetts GeneralBoston, Massachusetts, United StatesRecruiting
The Valley HospitalRidgewood, New Jersey, United StatesRecruiting
Ohio State University Medical CenterColumbus, Ohio, United StatesRecruiting
Kelowna General HospitalKelowna, British Columbia, CanadaRecruiting
Fraser Health AuthoritySurrey, British Columbia, CanadaRecruiting
University of British ColumbiaVancouver, British Columbia, CanadaNot Yet Recruiting
Dalhousie universityHalifax, Nova Scotia, CanadaNot Yet Recruiting
London Health Sciences CentreLondon, Ontario, CanadaRecruiting
University of Ottawa Heart InstituteOttawa, Ontario, CanadaRecruiting
University Health NetworkToronto, Ontario, CanadaRecruiting
Montreal Heart InstituteMontreal, Quebec, CanadaRecruiting
Institut universitaire de cardiologie et de pneumologie de QuébecQuébec, Quebec, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT02860364