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Study identifier: NCT02856620 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

The Role of Cardiac Mechanics, Biomarkers and Frailty in Aortic Stenosis

Condition: Heart Failure · Aortic Stenosis  ·  Sponsor: Christine Henri

PhaseN/A
Planned participants450
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

The role of cardiac mechanics, circulating biomarkers and frailty in predicting outcomes in patients with aortic stenosis after aortic valve replacement (SCRABLES -The 2-Parts Study) Part I: Observational study to characterize phenotypes, structural alterations and biomarkers profiles in a broad spectrum of patients with aortic stenosis and heart failure with preserved ejection fraction (HFpEF). Part II: Prospective cohort study to characterize patients' phenotypes, cardiac structural alterations, circulating biomarkers and frailty in order to optimize risk stratification and patient selection for aortic valve intervention.

This description comes directly from the study's public registry record.

Talk to the study team

Helene Brown, RN. B.Sc.  ·  514-376-3330  ·  helene.brown@icm-mhi.org

Always discuss trial participation with your own doctor first.

Locations (1)

Montreal Heart InstituteMontreal, Quebec, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT02856620