Condition: Bilateral Traumatic Amputation of Upper Limbs · Sponsor: Hospices Civils de Lyon
The double amputation of the forearms is a rare handicap that seriously impacts the autonomy and the quality of life of patients, social and familial exclusion, and dependence on third parties for everyday activities. The management of these patients is nearly exclusively through the use of prostheses. Certain patients refuse this solution, or remain penalized by the absence of sensitivity , the lack of precision in movements, and body image issues related to the amputation; the double graft of hands and forearms may, in this circumstance, be the only solution. Since January 2000, date of the first double hand graft, six bilateral grafts of hands have been performed at the Hospices Civils de Lyon. This first study reported the feasibility of the graft. The functional results obtained after the double transplant have allowed patients to recover complete autonomy for everyday activities, at the price of an immunosuppressive treatment. We have found that these very good functional results are maintained over time and, for a certain number of patients, to return to work which is a factor of social integration. The rate of medical complications (metabolic, infectious, oncological), essentially related to the immunosuppressive treatment, is not greater to that found for other types of graft, but are considered as a limiting factor for the development of this strategy. These results are confirmed by international experience that is of the same order. Only a few rare cases of re-a…
This description comes directly from the study's public registry record.
Lionel BADET, M · 4 72 11 91 91 · lionel.badet@chu-lyon.fr
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| Serice de Rééducation et Réadaptation fonctionnelles - Centre Jacques Calvé - Fondation Hopale | Berck, France | Recruiting |
| Service de Médecine Physique et Réadapatation fonctionnelle - Centre de Médecine Physique et de Réadaptation La Tour de Gassies | Bruges, France | Recruiting |
| Serice de Médecine Physique et Réadaptation - Hôpital d'Instruction des Armées Percy | Clamart, France | Recruiting |
| Serice de Rééducation et Réadaptation fonctionnelles - Centre l'Espoir | Lille, France | Recruiting |
| Serice de Médecine Physique et Réadaptation des patients amputés - Centre Médico-Chirugical et de Réadaptation des Massues | Lyon, France | Recruiting |
| Service de Chirurgie de la Transplantation - Hôpital Edouard Herriot - Hospices Civils de Lyon | Lyon, France | Recruiting |
| Serice de Rééducation et Réadaptation fonctionnelles - Centre Médical de Rééducation Romans Ferrari | Miribel, France | Recruiting |
| Service de Médecine Physique et Réadaptation - Institut Régional de Médecine Physique et de Réadaptation | Nancy, France | Recruiting |
| Serice de Rééducation fonctionnelle - Centre Mutualiste de Rééducation et Réadaptation fonctionnelles de Kerpape | Ploemeur, France | Recruiting |
| Serice de Rééducation et Réadaptation fonctionnelles - Hôpital Henry-Gabrielle - Hospices Civils de Lyon | Saint-Genis-Laval, France | Recruiting |
| Service de Rééducation et appareillage - Institut Robert Merle d'Aubigné | Valenton, France | Recruiting |
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Source record: clinicaltrials.gov/study/NCT02797457