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Study identifier: NCT02781883 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Clinical Trial of BP1001 in Combination With With Venetoclax Plus Decitabine in AML

Condition: Acute Myeloid Leukemia (AML)  ·  Sponsor: Bio-Path Holdings, Inc.

PhasePhase 2
Planned participants108
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The primary objectives of this study are to assess: (1) whether the combination of BP1001 plus venetoclax plus decitabine provides greater efficacy (Complete Remission \[CR\], Complete Remission with incomplete hematologic recovery \[CRi\], Complete Remission with partial hematologic recovery \[CRh\], than venetoclax plus decitabine alone (by historical comparison) in participants with untreated AML that cannot or elect not to be treated with more intensive chemotherapy; (2) whether BP1001-based treatment provides greater efficacy (CR, CRi, CRh) than intensive chemotherapy (by historical comparison) in participants with refractory/relapsed AML.

This description comes directly from the study's public registry record.

Talk to the study team

Maro Ohanian, DO  ·  713-792-2631  ·  mohanian@mdanderson.org

Always discuss trial participation with your own doctor first.

Locations (9)

UCLA Medical CenterLos Angeles, California, United StatesRecruiting
Georgia Cancer Center at Augusta UniversityAugusta, Georgia, United StatesRecruiting
University of Kansas Cancer CenterFairway, Kansas, United StatesRecruiting
New Jersey Hematology Oncology AssociatesBrick, New Jersey, United StatesTerminated
Laura & Isaac Pe lmutter Cancer Center at NYU Langone HealthNew York, New York, United StatesRecruiting
Weill Cornell Medical College - New York - Presbyterian HospitalNew York, New York, United StatesRecruiting
University of Texas M.D. Anderson Cancer CenterHouston, Texas, United StatesRecruiting
Baylor Scott & White Research InstituteTemple, Texas, United StatesTerminated
West Virginia University/Mary Babb Randolph Cancer CenterMorgantown, West Virginia, United StatesTerminated

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Source record: clinicaltrials.gov/study/NCT02781883