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Study identifier: NCT02691923 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Diagnostic Performance of Fluorescein as an Intraoperative Brain Tumor Biomarker

Condition: Brain Cancer  ·  Sponsor: David W. Roberts

PhasePhase 2
Planned participants30
Who can joinAll sexes, 21 Years to no upper limit
Healthy volunteersNo

About this study

This clinical research will evaluate the diagnostic potential of fluorescein as visualized through an operating microscope relative to 1) contrast enhancement on co-registered preoperative MR scans, 2) intraoperative ALA-induced PpIX fluorescence and 3) gold-standard histology obtained from biopsy sampling during the procedure. Subjects will include those people with operable brain tumor with first-time presumed pre-surgical diagnosis of high-grade glioma or low-grade glioma.

This description comes directly from the study's public registry record.

Talk to the study team

Sally B Mansur, MS  ·  Sally.B.Mansur@Dartmouth.edu

Keith D Paulsen, PhD  ·  Keith.D.Paulsen@Dartmouth.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Sally B MansurLebanon, New Hampshire, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT02691923