Condition: Breast Cancer Screening · Breast Carcinoma in Situ · Breast Cancer · Sponsor: University of California, San Francisco
Most physicians still use a one-size-fits-all approach to breast screening in which all women, regardless of their personal history, family history or genetics (except BRCA carriers) are recommended to have annual mammograms starting at age 40. Mammograms benefit women by detecting cancers early when they are easier to treat, but they are not perfect. Recent news stories have discussed some of the potential harms: large numbers of positive results that cause stressful recalls for additional mammograms and biopsies. With the current screening approach, half of the women who undergo annual screening for ten years will have at least one false positive biopsy. Potentially more important are cancer diagnoses for growths that might never come to clinical attention if left alone (called "overdiagnosis"). This can lead to unnecessary treatment. Even more concerning is evidence that up to 20% of breast cancers detected today may fall into the category of "overdiagnosis." The WISDOM 1.0 study compares annual screening with a risk-based breast cancer screening schedule, based upon each woman's personal risk of breast cancer. The investigators have designed the study to be inclusive of all, so that even women who might be nervous about being randomly assigned to receive a particular type of care (a procedure that is typical in clinical studies) will still be able to participate by choosing the type of care they receive. For participants in the risk-based screening arm, each woman will …
This description comes directly from the study's public registry record.
Allison Fiscalini, MPH · (415) 476-0267 · allison.stoverfiscalini@ucsf.edu
Jennifer Atamer · Jennifer.atamer@ucsf.edu
Always discuss trial participation with your own doctor first.
| University of Alabama at Birmingham | Birmingham, Alabama, United States | Recruiting |
| University of California Irvine | Irvine, California, United States | Recruiting |
| University of California Los Angeles | Los Angeles, California, United States | Recruiting |
| University of California Davis | Sacramento, California, United States | Recruiting |
| University of California San Diego | San Diego, California, United States | Recruiting |
| University of California San Francisco | San Francisco, California, United States | Recruiting |
| TopLine MD Alliance | Miami, Florida, United States | Recruiting |
| University of Chicago | Chicago, Illinois, United States | Recruiting |
| Louisiana State University | New Orleans, Louisiana, United States | Active Not Recruiting |
| Weill Cornell Medicine | New York, New York, United States | Recruiting |
| Edith Sanford Breast Center | Sioux Falls, South Dakota, United States | Active Not Recruiting |
Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.
We email about this public record only. Unsubscribe anytime with one click. Never medical advice.
This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.
Source record: clinicaltrials.gov/study/NCT02620852