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Study identifier: NCT02598349 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Proton Radiation for Unresectable, Borderline Resectable, or Medically Inoperable Carcinoma of the Pancreas

Condition: Pancreatic Cancer  ·  Sponsor: Proton Collaborative Group

PhasePhase 2
Planned participants60
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The prognosis for patients with localized pancreatic adenocarcinoma who are not surgical candidates is poor. Patients characterized as having "borderline resectable" disease treated with preoperative chemo-radiotherapy fair somewhat better - although many of these patients are not converted to resectability. It may be argued that intensification of local and regional therapy might 1.) Increase the share of patients able to undergo curative surgery and 2.) Improve the local disease control interval and extend survival for patients who remain unresectable. Therefore, the purpose of this research study is to determine if an increase in the number of surgical resection pancreatic adenocarcinoma is higher than historical data by using a combined treatment of proton radiation with capecitabine (oral chemotherapy).

This description comes directly from the study's public registry record.

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Contact details are listed per location below or on the registry record.

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Locations (4)

University of Florida Proton Therapy InstituteJacksonville, Florida, United StatesActive Not Recruiting
Northwestern Medicine Chicago Proton CenterWarrenville, Illinois, United StatesRecruiting
McLaren Proton Therapy CenterFlint, Michigan, United StatesRecruiting
Inova Schar Cancer InstituteFairfax, Virginia, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT02598349