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Study identifier: NCT02523014 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas

Condition: Intracranial Meningioma · Recurrent Meningioma · NF2 Gene Mutation  ·  Sponsor: Alliance for Clinical Trials in Oncology

PhasePhase 2
Planned participants124
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This phase II trial studies how well vismodegib, focal adhesion kinase (FAK) inhibitor GSK2256098, and capivasertib work in treating patients with meningioma that is growing, spreading, or getting worse (progressive). Vismodegib, FAK inhibitor GSK2256098, capivasertib, and abemaciclib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

This description comes directly from the study's public registry record.

Talk to the study team

Priscilla Brastianos, MD  ·  617-643-1939

Always discuss trial participation with your own doctor first.

Locations (780)

University of Alabama at Birmingham Cancer CenterBirmingham, Alabama, United StatesActive Not Recruiting
Anchorage Associates in Radiation MedicineAnchorage, Alaska, United StatesRecruiting
Anchorage Radiation Therapy CenterAnchorage, Alaska, United StatesSuspended
Alaska Breast Care and Surgery LLCAnchorage, Alaska, United StatesRecruiting
Alaska Oncology and Hematology LLCAnchorage, Alaska, United StatesRecruiting
Alaska Women's Cancer CareAnchorage, Alaska, United StatesRecruiting
Anchorage Oncology CentreAnchorage, Alaska, United StatesSuspended
Katmai Oncology GroupAnchorage, Alaska, United StatesRecruiting
Providence Alaska Medical CenterAnchorage, Alaska, United StatesRecruiting
Fairbanks Memorial HospitalFairbanks, Alaska, United StatesRecruiting
Kingman Regional Medical CenterKingman, Arizona, United StatesRecruiting
Cancer Center at Saint Joseph'sPhoenix, Arizona, United StatesRecruiting

+ 768 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT02523014