← Eichor
Study identifier: NCT02521311 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Assessment of Clemastine Fumarate as a Remyelinating Agent in Acute Optic Neuritis (ReCOVER)

Condition: Optic Neuritis  ·  Sponsor: University of California, San Francisco

PhasePhase 2
Planned participants90
Who can joinAll sexes, 18 Years to 55 Years
Healthy volunteersNo

About this study

The main purpose of this study is to assess clemastine as a remyelinating agent in patients with acute optic neuritis.The study will also evaluate the tolerability of clemastine, originally approved as first-generation antihistamine, in patients with optic neuritis. Study procedures will include assessments for evidence of remyelination in the anterior visual pathway and in the brain using electrophysiologic techniques and magnetic resonance imaging. If they are on one, patients in this study can remain on their standard disease modifying treatment during the course of the study. However, patients cannot participate in any other investigational new drug research study concurrently.

This description comes directly from the study's public registry record.

Talk to the study team

Harkeerat Halait  ·  415.353.2707  ·  Harkeerat.Halait@ucsf.edu

Angelica Montevirgen, BS  ·  415.745.1304  ·  Angelica.Montevirgen@ucsf.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of California San FranciscoSan Francisco, California, United StatesRecruiting

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT02521311