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Study identifier: NCT02507141 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Reflectance Confocal Microscopy of Oral Cancers in Vivo: a Preliminary Trial Comparing Intra-oral Imaging With Pathology

Condition: Head and Neck Cancer · Squamous Cell Carcinoma (SCC) of the Oral Cavity  ·  Sponsor: Memorial Sloan Kettering Cancer Center

PhaseN/A
Planned participants140
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to get images (pictures) of oral lesions, which occur inside the mouth, before the patient's surgery using a special camera. These pictures will be used in our research to evaluate a new technology that uses a laser and takes pictures of the microscopic structure of tissue. The technology is called "reflectance confocal microscopy." We would like to compare what the camera sees to biopsies (pathology) of the same area. We will evaluate the pictures obtained from the patient to determine whether this technology may be useful in the future. We hope this technology can be used as a tool for early diagnosis of oral cancers and for guiding surgery.

This description comes directly from the study's public registry record.

Talk to the study team

Snehal Patel, MD  ·  212-639-3412

Milind Rajadhyaksha, PhD  ·  646-888-6243

Always discuss trial participation with your own doctor first.

Locations (5)

Memorial Sloan Kettering Basking Ridge (consent only)Basking Ridge, New Jersey, United StatesRecruiting
Memorial Sloan Kettering Monmouth (consent only)Middletown, New Jersey, United StatesRecruiting
Memorial Sloan Kettering West Harrison (consent only)Harrison, New York, United StatesRecruiting
Memorial Sloan Kettering Cancer CenterNew York, New York, United StatesRecruiting
Memorial Sloan Kettering Nassau (consent only)Uniondale, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT02507141