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Study identifier: NCT02476786 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Endocrine Treatment Alone for Elderly Patients With Estrogen Receptor Positive Operable Breast Cancer and Low Recurrence Score

Condition: Breast Cancer · Cancer of Breast · Breast Neoplasms  ·  Sponsor: Washington University School of Medicine

PhasePhase 2
Planned participants50
Who can joinFemale, 70 Years to no upper limit
Healthy volunteersNo

About this study

Multiple neoadjuvant endocrine trials demonstrate that women with good prognosis tumors can be identified. These trials have also demonstrated that there are not adverse effects on overall outcome if women are treated with neoadjuvant endocrine therapy for several months prior to definitive treatment. A new standard of care needs to be defined for elderly women with good prognosis estrogen receptor (ER)+ tumors, since these women may benefit from endocrine therapy alone to treat their cancer without compromising local and distant control. The investigators hypothesize that endocrine therapy alone provides adequate local and systemic control of breast cancer in a subpopulation of women 70 or older with ER+ breast cancer and low Ki67 scores.

This description comes directly from the study's public registry record.

Talk to the study team

Rebecca L Aft, M.D., Ph.D.  ·  314-747-0063  ·  aftr@wustl.edu

Tracie Guthrie  ·  314-747-4404  ·  guthriet@wustl.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Washington University School of MedicineSt Louis, Missouri, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT02476786