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Study identifier: NCT02461446 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Natural History Study of Individuals With Autism and Germline Heterozygous PTEN Mutations

Condition: PTEN · ASD · Autism  ·  Sponsor: Boston Children's Hospital

PhaseN/A
Planned participants170
Who can joinAll sexes, 18 Months to no upper limit
Healthy volunteersYes

About this study

The purpose of this study is to determine cross-sectional and longitudinal medical, behavioral, and cognitive differences between PTEN ASD and other groups, as well as to identify cognitive, neural systems, and molecular biomarkers specific to PTEN ASD. In addition, this study will be creating and maintaining a biorepository and linked phenotypic database for PTEN ASD.

This description comes directly from the study's public registry record.

Talk to the study team

Rajna Filip-Dhima, MS  ·  617-919-7068  ·  Rajna.Filip-Dhima@childrens.harvard.edu

Always discuss trial participation with your own doctor first.

Locations (5)

University of California at Los AngelesLos Angeles, California, United StatesRecruiting
Stanford University Medical CenterStanford, California, United StatesRecruiting
Boston Children's HospitalBoston, Massachusetts, United StatesRecruiting
Cincinnati Children's Hospital Medical CenterCincinnati, Ohio, United StatesRecruiting
Cleveland ClinicCleveland, Ohio, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT02461446