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Study identifier: NCT02423213 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

DISCOVER Study: Microscope-integrated Intraoperative OCT Study

Condition: Retinal Diseases · Fuchs Endothelial Dystrophy · Macular Hole  ·  Sponsor: The Cleveland Clinic

PhaseN/A
Planned participants3000
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

Optical coherence tomography (OCT )provides high resolution information regarding the anatomic structure of the tissues of the eye in a cross-sectional and 3 dimensional view. Much of this information is not able to be visualized by a clinician. Utilizing this information during surgery will allow for the ophthalmic surgeons to better understand how surgical procedures impact the anatomic structure of the eye. In this study an OCT device that has been built into the microscope (rather than mounted on the side or held in the surgeon's hand) and will be utilized to take images at various milestones during surgery to assess feasibility and potential utility of this technology. Since it is built into the microscope, there are potential significant advantages over a separate system including increased efficiency, improved working distance, and the ability to visualize tissue-instrument interactions.

This description comes directly from the study's public registry record.

Talk to the study team

Justis P Ehlers, M.D.  ·  216-636-0183  ·  ehlersj@ccf.org

Jamie L Reese, R.N.  ·  216-636-0183  ·  reesej3@ccf.org

Always discuss trial participation with your own doctor first.

Locations (1)

Cole Eye Institute, Cleveland ClinicCleveland, Ohio, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT02423213