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Study identifier: NCT02399137 Synced from ClinicalTrials.gov · July 28, 2026
● Completed

A Phase 2 Study of MM-141 Plus Nab-paclitaxel and Gemcitabine in Front-line Metastatic Pancreatic Cancer

Condition: Pancreatic Cancer  ·  Sponsor: Merrimack Pharmaceuticals

PhasePhase 2
Planned participants88
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to determine whether the combination of MM-141 plus nab-paclitaxel and gemcitabine is more effective than nab-paclitaxel and gemcitabine alone based on Progression Free Survival (PFS) in front-line metastatic pancreatic cancer patients with high serum levels of free IGF-1.

This description comes directly from the study's public registry record.

Talk to the study team

Contact details are listed per location below or on the registry record.

Always discuss trial participation with your own doctor first.

Locations (66)

Banner MD Anderson Cancer Ctr.Gilbert, Arizona, United States
Pacific Cancer Medical Center, Inc.Anaheim, California, United States
St. Jude Heritage HealthcareFullerton, California, United States
UCLA School of MedicineLos Angeles, California, United States
Cancer Care Assoc Med GrpRedondo Beach, California, United States
UCSF Cancer CenterSan Francisco, California, United States
Sansum ClinicSanta Barbara, California, United States
Central Coast Med Onc CorpSanta Maria, California, United States
Rocky Mountain Cancer CentersAurora, Colorado, United States
Baptist Health Med Gr Onc, LLCMiami, Florida, United States
Florida Cancer AffiliatesOcalaOcala, Florida, United States
Memorial Regional HospitalPembroke Pines, Florida, United States

+ 54 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT02399137