Condition: Low Grade Glioma · Sponsor: James Felker
The study will assess the immunogenicity, safety and preliminary clinical efficacy of the glioma associated antigen (GAA)/tetanus toxoid (TT) peptide vaccine and poly-ICLC in HLA-A2+ children with unresectable low-grade gliomas that have received at least two chemotherapy/biologic regimens. Radiation therapy counts as one biologic regimen, but patients may not have received radiation to the index lesion within 1 year of enrollment.
This description comes directly from the study's public registry record.
James Felker, MD · 412 692-5055
Sharon Dibridge · 412-692-7070 · sharon.dibridge@chp.edu
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| Children's Hospital of Pittsburgh of UPMC | Pittsburgh, Pennsylvania, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT02358187