Condition: Rare Histiocytic Disorders (RHDs) · Erdheim-Chester Disease (ECD) · Rosai-Dorfman Disease (RDD) · Sponsor: The Hospital for Sick Children
The rare histiocytic disorders (RHDs) are characterized by the infiltration of one or more organs by non-LCH histiocytes. They can range from localized disease that resolves spontaneously, to progressive disseminated forms that can be sometimes life-threatening. Since they are extremely rare, there is limited understanding of their causes and best treatment options. Physicians, patients and parents of children with RHDs frequently consult members of the Histiocyte Society regarding the best management of these disorders. Very often, no specific recommendation can be made due to the lack of prospective outcome data, or even large retrospective case series. The creation of an international rare histiocytic disorders registry (IRHDR) could facilitate a uniform diagnosis of the RHDs, as well as the collection and analysis of the clinical, epidemiological, treatment and survival data of patients with RHD. The registry may also lead to future therapeutic recommendations, provide a framework for future clinical trials and create excellent research opportunities.
This description comes directly from the study's public registry record.
Oussama Abla, MD · 416-813-7879 · oussama.abla@sickkids.ca
Always discuss trial participation with your own doctor first.
| The University of Alabama at Birmingham | Birmingham, Alabama, United States | Recruiting |
| Children's Hospital of Los Angeles | Los Angeles, California, United States | Recruiting |
| Valley Children's Hospital | Madera, California, United States | Recruiting |
| Dana-Farber Cancer Institute | Boston, Massachusetts, United States | Recruiting |
| Memorial Sloan Kettering Cancer Center | New York, New York, United States | Recruiting |
| University of Pittsburgh Medical Center | Pittsburgh, Pennsylvania, United States | Recruiting |
| Hospital Nacional de Pediatria Garrahan | Buenos Aires, Argentina | Recruiting |
| The Hospital for Sick Children | Toronto, Ontario, Canada | Recruiting |
| Centre hospitalier universitaire Sainte-Justine | Montreal, Quebec, Canada | Active Not Recruiting |
| University Hospital Brno | Brno, Czechia | Recruiting |
| Rostock University Medical Hospital | Rostock, Germany | Recruiting |
| Azienda Ospedaliero-Universitaria Meyer | Florence, Italy | Recruiting |
+ 3 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT02285582