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Study identifier: NCT02232191 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Immunologic Response to Pneumococcal Polysaccharide Vaccine in Splenic Injury Patients

Condition: Asplenia  ·  Sponsor: University of California, Davis

PhasePhase 2
Planned participants75
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

Persons without a spleen are susceptible to potentially lethal infections from certain bacteria, with pneumococcus being the most prevalent. Vaccines are provided to help protect against these infections, though they do not so with certainty. Trauma patients who sustain an injury to their spleen currently have three treatment options available for the treating surgeon - nonoperative management, embolization, or removal of the spleen. The purpose of this study is to investigate the antibody response to pneumococcal vaccine in patients undergoing these modes of therapy.

This description comes directly from the study's public registry record.

Talk to the study team

David V Shatz, MD  ·  916-734-5535  ·  dvshatz@ucdavis.edu

Anthony Calabro, PhD  ·  916-734-4365  ·  arcalabro@ucdavis.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of California, Davis Medical CenterSacramento, California, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT02232191